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Peter W M Johnson Selected Research

3-deazaadenosine

5/2011S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition.

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Peter W M Johnson Research Topics

Disease

31Neoplasms (Cancer)
01/2022 - 09/2002
19Lymphoma (Lymphomas)
01/2022 - 09/2002
15Hodgkin Disease (Hodgkin's Disease)
01/2022 - 12/2005
13B-Cell Lymphoma (Lymphoma, B Cell)
01/2019 - 01/2003
6Breast Neoplasms (Breast Cancer)
01/2022 - 08/2003
4Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2020 - 10/2017
3Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
10/2017 - 03/2006
3B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
05/2017 - 09/2011
2Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
02/2016 - 09/2011
1Carcinoma (Carcinomatosis)
01/2022
1Sickle Cell Anemia (Hemoglobin S Disease)
01/2021
1Acquired Immunodeficiency Syndrome (AIDS)
01/2021
1COVID-19
01/2021
1Dementia (Dementias)
01/2021
1Down Syndrome (Down's Syndrome)
01/2021
1Parkinson Disease (Parkinson's Disease)
01/2021
1Liver Cirrhosis (Hepatic Cirrhosis)
01/2021
1Burkitt Lymphoma (Burkitt's Lymphoma)
01/2019
1Lymphocytosis
06/2015
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2012
1Thrombosis (Thrombus)
01/2012
1Febrile Neutropenia
01/2012
1Sepsis (Septicemia)
01/2012
1Prostatic Neoplasms (Prostate Cancer)
03/2008

Drug/Important Bio-Agent (IBA)

10Rituximab (Mabthera)FDA Link
01/2022 - 02/2009
7Monoclonal AntibodiesIBA
12/2017 - 02/2003
6Proteins (Proteins, Gene)FDA Link
01/2020 - 09/2002
5Doxorubicin (Adriamycin)FDA LinkGeneric
10/2018 - 12/2005
4Biological ProductsIBA
01/2019 - 08/2008
4Bleomycin (Blenoxane)FDA LinkGeneric
10/2018 - 12/2005
4Dacarbazine (DIC)FDA LinkGeneric
10/2018 - 12/2005
4Vinblastine (Vinblastine Sulfate)FDA Link
10/2018 - 12/2005
3Biomarkers (Surrogate Marker)IBA
01/2022 - 09/2002
3Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
10/2017 - 06/2014
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
11/2016 - 02/2016
2VaccinesIBA
01/2022 - 01/2021
2AntigensIBA
01/2022 - 11/2018
2Immunoglobulin G (IgG)IBA
11/2018 - 08/2014
2AntibodiesIBA
11/2018 - 04/2015
2varlilumabIBA
11/2018 - 12/2017
2Vincristine (Oncovin)FDA LinkGeneric
11/2016 - 07/2016
2Histone Deacetylases (Histone Deacetylase)IBA
05/2011 - 08/2008
2Histone Deacetylase InhibitorsIBA
05/2011 - 08/2008
1obinutuzumabIBA
01/2022
1COVID-19 VaccinesIBA
01/2022
1Trastuzumab (Herceptin)FDA Link
01/2022
1venetoclaxIBA
01/2020
1PLX51107IBA
01/2020
1BenzodiazepinesIBA
01/2020
1GSK-2816126IBA
12/2019
1Enhancer of Zeste Homolog 2 ProteinIBA
12/2019
1Bortezomib (Velcade)FDA Link
01/2019
1Blocking AntibodiesIBA
12/2018
1Immunoconjugates (Immunoconjugate)IBA
12/2018
1Member 9 Tumor Necrosis Factor Receptor SuperfamilyIBA
11/2018
1Phosphotransferases (Kinase)IBA
05/2017
1ibrutinibIBA
05/2017
1Janus Kinase InhibitorsIBA
05/2017
14- (cyclopropylamino)- 2- ((4- (4- (ethylsulfonyl)piperazin- 1- yl)phenyl)amino)pyrimidine- 5- carboxamideIBA
05/2017
1Prednisolone (Predate)FDA LinkGeneric
11/2016
1Etoposide (VP 16)FDA LinkGeneric
07/2016
1Procarbazine (Matulane)FDA Link
07/2016
1Prednisone (Sone)FDA LinkGeneric
07/2016
1ibritumomab tiuxetan (Zevalin)FDA Link
04/2016
1fludarabineIBA
02/2016
12- amino- 8- (4- (2- hydroxyethoxy)cyclohexyl)- 6- (6- methoxypyridin- 3- yl)- 4- methylpyrido(2,3- d)pyrimidin- 7(8H)- oneIBA
06/2015
1IpilimumabIBA
08/2014
1AnthracyclinesIBA
06/2014
1Irinotecan (Camptosar)FDA LinkGeneric
01/2012
1Carboplatin (JM8)FDA LinkGeneric
01/2012
1neplanocin AIBA
05/2011
1theasinensin AIBA
05/2011
1AdenosylhomocysteinaseIBA
05/2011
13-deazaneplanocinIBA
05/2011
1HydrolasesIBA
05/2011
1trichostatin A (A 300)IBA
05/2011
13-deazaadenosineIBA
05/2011
1Histone MethyltransferasesIBA
05/2011
1Peptides (Polypeptides)IBA
11/2009
1spiruchostatin AIBA
08/2008
1DepsipeptidesIBA
08/2008
1romidepsin (FK228)FDA Link
08/2008
1Cyproterone AcetateIBA
03/2008
1Glucose (Dextrose)FDA LinkGeneric
03/2008
1LipidsIBA
03/2008
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
03/2008
1PPAR gammaIBA
03/2008

Therapy/Procedure

24Therapeutics
01/2022 - 09/2002
12Drug Therapy (Chemotherapy)
01/2021 - 01/2008
6Radiotherapy
01/2021 - 07/2010
3Radioimmunotherapy
04/2016 - 02/2004
2Precision Medicine
06/2021 - 10/2017
1Salvage Therapy
01/2022
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2021
1Kidney Transplantation
01/2021
1Organ Transplantation
01/2021
1Chemoradiotherapy
12/2018
1Ligation
05/2013
1Combination Drug Therapy (Combination Chemotherapy)
01/2013
1Immunotherapy
08/2006